Semaglutide is an FDA-approved medication developed for management of type-2 diabetes. The drug was developed by Novo Nordisk, one of the world’s largest pharmaceutical companies and released in 2017. Novo Nordisk specializes in the development of drugs called GLP-1’s, which have been shown to work well in managing insulin levels in type-2 diabetics. Novo Nordisk developed drugs called Wegovy and Rybelsus, both based on a molecule called “semaglutide.” They discovered that in overweight or obese diabetic patients, these drugs curbed appetites and led to remarkable weight loss properties.
Semaglutide works by simulating the effects of the hormone your body produces when you eat food, called incretin. After you eat a big meal, your body releases incretin which signals the feeling of fullness and tells your brain to stop eating. In addition, it also helps to prevent the effects of insulin resistance which also contributes to a feeling of fullness and reduces cravings for sugary or unhealthy foods. Coupled with diet and exercise, Semaglutide has been shown to have remarkable weight loss properties.
Semaglutide is taken as a once-weekly injection. You simply draw up the directed amount by your doctor an inject with an extremely small gauge needle (insulin syringe) into your stomach or thigh. Injection is relatively painless. You also only need to inject once a week, with no pills or other required medicines at other times.
Clinical studies have shown as much as ~16% weight-loss over a one year period, with the majority of the weight-loss happening earlier in the program (within the first 6 months). When coupled with your easy to follow food and fitness plan, your weight-loss could be considerably higher. With any weight-loss program, it will still be important to change your lifestyle and exercise will-power. However, the medication will make this process significantly easier.
The most common side effects of Semaglutide are nausea and GI-related side effects. Your doctor may prescribe you an anti-nausea medication while you take the drug to reduce these side effects. There are several positive side-effects of Semaglutide , such as reduced A1C levels and reduced risk for heart disease. There are some rare and potentially serious side effects of Semaglutide that your doctor will discuss based on your family and medical history to determine if the drug is right for you.
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